Search results for "Fibrin matrix"

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How to Improve the Uterotomy Healing

1994

Abstract Suboptimal uterotomy healing following cesarean delivery or metroplastic operations may lead to considerable complications. New insights in the biology of wound healing and the availability of a variety of biologic response modifiers open the possibility to modulate the process of wound healing in order to gain clinical benefits. Can uterotomy healing be improved by local application of biosubstances? We developed an uterotomy model in the rat and measured the bursting pressure at defined times postwounding as a functional parameter of wound healing. In addition, the healing process was assessed by serial light microscopic histology. Uterotomy healing was investigated in the presen…

Pathologymedicine.medical_specialtybiologyBiologic responsebusiness.industryFibrin matrixFibrinAnesthesiabiology.proteinmedicineSurgeryTumor necrosis factor alphaCesarean deliveryWound healingbusinessTumor necrosis factor αWound hemorrhageJournal of Surgical Research
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Comparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions : a randomized controlled trial

2019

Background Titanium- prepared platelet rich fibrin (T-PRF) is an autologous hemo-component with a high concentration of platelets that also incorporates leukocytes, and growth factors into the dense fibrin matrix and can be used as a healing biomaterial. This study assesses the adjunctive use of T-PRF in intrabony defects (IBDs) with open flap debridement (OFD) in comparison with guided tissue regeneration (GTR) as a gold standard and OFD alone as a control. Material and Methods A total of 45 patients (15 per group) were randomized as either T-PRF (test group), GTR (test group), or OFD alone (control group) sites. Probing depth (PD), clinical attachment level (CAL), and IBD were recorded. T…

Test groupmedicine.medical_treatmentAlveolar Bone LossFibrin matrixDentistrylaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawPlatelet-Rich FibrinmedicineHumansPeriodontologyPeriodontitisFlap SurgeryGeneral DentistryTitaniumGuided Tissue Regenerationbusiness.industryResearchSignificant differenceOpen flap debridementIntrabony DefectsAttachment level030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Platelet-rich fibrindigestive system diseasesRoot Canal TherapyTreatment OutcomeDebridementOtorhinolaryngologyDebridement (dental)UNESCO::CIENCIAS MÉDICASGuided Tissue Regeneration PeriodontalSurgerybusiness
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